Prostaglandins mediate the cardioprotective effects of atorvastatin against ischemia?reperfusion injury
نویسندگان
چکیده
منابع مشابه
Prostaglandins mediate the cardioprotective effects of atorvastatin against ischemia-reperfusion injury.
OBJECTIVES Statins attenuate myocardial ischemic injury by activating nitric oxide synthase (NOS). It is unknown whether cyclooxygenase-2 (COX2), which mediates late ischemic preconditioning, also mediates statins-induced cardioprotection. We investigated the involvement of the prostaglandins and NOS in the cardioprotective effect of atorvastatin (ATV) in the rat. METHODS Sprague-Dawley rats ...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2005
ISSN: 0008-6363
DOI: 10.1016/j.cardiores.2004.10.018